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Stevia aqueous extract (400 mg⋅kg –1 ) exerts nephroprotective effects by regulating the expression of AQP2 mRNA and the activity of the antioxidant signaling pathway Nrf2/Kelch-like ECH-associated protein 1 in the kidneys ( To maximize stevia’s therapeutic potential, research should explore the synergistic effects of stevia when combined with existing anti-diabetic or anti-hypertensive medications, aiming to enhance efficacy and minimize adverse effects

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That is reasoning from mechanism, not evidence, and it is not a basis for assuming either safety or risk alongside anything else